Featured Technology
ENGINEERING A SINGLE CHAIN ANTIBODY-BASED BIOLOGIC ARMED WTH AN APOPTOTIC EXECUTOR
Tumor specific antigens (TSAs) escape detection, thus allowing the tumor to grow unimpeded. The authors of this article propose that TSA targeted therapeutics are within reach and will be: (i) able to penetrate cells via a universal entry point; (ii) able to specifically bind to a TSA; and (iii) in response to the binding event trigger a cellular response,
preferably leading to the death of the tumor cell. From an engineering standpoint, the authors argue that this can
be accomplished by assembling three components in a logical way such that the detection of a Tumor Specific Antigen
within a cell leads to the induction of a desired downstream event; apoptosis.
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Featured Press Release
TriLink Enters into Distribution Agreement with Sigma-Aldrich
TriLink announced that it has entered into a distribution agreement with Sigma-Aldrich to sell its CleanAmp™ dNTPs globally.
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Biotech Market Summary
| symbol | last price | date | time | change | open | high | low | volume |
|---|---|---|---|---|---|---|---|---|
| AFFY | 10.23 | 2/22/2012 | 3:03pm | -0.17 | 10.43 | 10.4425 | 10.05 | 820819 |
| ILMN | 50.86 | 2/22/2012 | 3:03pm | -0.59 | 51.11 | 51.64 | 50.56 | 2139420 |
| ARNA | 1.76 | 2/22/2012 | 3:03pm | -0.04 | 1.86 | 1.87 | 1.74 | 2920626 |
| VRUS | 0.00 | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| GENZ | 0.00 | N/A | N/A | N/A | N/A | N/A | N/A | N/A |
| A | 42.74 | 2/22/2012 | 3:04pm | +0.13 | 42.45 | 43.29 | 42.34 | 1658042 |
| MRK | 38.145 | 2/22/2012 | 3:04pm | +0.015 | 38.06 | 38.19 | 37.90 | 6717554 |

